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Dual Role of Phenyl Amides from Hempseed on BACE 1, PPARγ, and PGC-1α in N2a-APP Cells
[Image: see text] In Alzheimer’s disease (AD) the accumulation of amyloid β (Aβ) plaques in the brain leads to neuroinflammation, neuronal cell dysfunction, and progressive memory loss. Therefore, blocking the formation of Aβ plaques has emerged as one of the most promising strategies to develop AD...
Autores principales: | Rea Martinez, Julio, Šelo, Gordana, Fernández-Arche, María Ángeles, Bermudez, Beatriz, García-Giménez, María Dolores |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society and American Society of Pharmacognosy
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610369/ https://www.ncbi.nlm.nih.gov/pubmed/34460260 http://dx.doi.org/10.1021/acs.jnatprod.1c00435 |
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