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Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A

Variants in the high confident autism spectrum disorder (ASD) gene ANK2 target both ubiquitously expressed 220 kDa ankyrin-B and neurospecific 440 kDa ankyrin-B (AnkB440) isoforms. Previous work showed that knock-in mice expressing an ASD-linked Ank2 variant yielding a truncated AnkB440 product exhi...

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Detalles Bibliográficos
Autores principales:	Creighton, Blake A, Afriyie, Simone, Ajit, Deepa, Casingal, Cristine R, Voos, Kayleigh M, Reger, Joan, Burch, April M, Dyne, Eric, Bay, Julia, Huang, Jeffrey K, Anton, ES, Fu, Meng-Meng, Lorenzo, Damaris N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610419/ https://www.ncbi.nlm.nih.gov/pubmed/34812142 http://dx.doi.org/10.7554/eLife.69815

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