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Pheochromocytoma Leading to Multiorgan Failure in a Pregnant Patient: A Case Report

INTRODUCTION: Pheochromocytoma, a neuroendocrine tumor that secretes catecholamines, can present with episodic sweating, diaphoresis, headaches, and hypertension, as well as cardiac and pulmonary involvement. In a pregnant patient, it must be differentiated from preeclampsia, a leading cause of mate...

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Detalles Bibliográficos
Autores principales: Myatt, Toby, Barker, Margot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: University of California Irvine, Department of Emergency Medicine publishing Western Journal of Emergency Medicine 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610485/
https://www.ncbi.nlm.nih.gov/pubmed/34813427
http://dx.doi.org/10.5811/cpcem.2021.6.52727
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author Myatt, Toby
Barker, Margot
author_facet Myatt, Toby
Barker, Margot
author_sort Myatt, Toby
collection PubMed
description INTRODUCTION: Pheochromocytoma, a neuroendocrine tumor that secretes catecholamines, can present with episodic sweating, diaphoresis, headaches, and hypertension, as well as cardiac and pulmonary involvement. In a pregnant patient, it must be differentiated from preeclampsia, a leading cause of maternal mortality in the developed world, which can similarly present with hypertension and multiorgan involvement. Both conditions require early diagnosis and treatment to reduce maternal and fetal morbidity and mortality. CASE REPORT: We discuss the case of a pregnant patient at approximately 24 weeks’ gestation presenting with chest pain and shortness of breath who was found to have a left adrenal mass and hypertensive urgency. The patient acutely decompensated during the course of evaluation. She ultimately suffered pregnancy loss and multiorgan failure requiring percutaneous heart pump placement and extracorporeal membrane oxygenation therapy for support before fully recovering. The adrenal mass was confirmed to be a pheochromocytoma after excision and contributed to the development of hypertensive emergency with multiorgan failure. CONCLUSION: Pheochromocytoma during pregnancy is a rare condition but must remain on the differential until ruled out to improve patient outcomes as much as possible. Obtaining blood pressure control is imperative to reducing maternal and fetal mortality. Preeclampsia is similarly serious, and early diagnosis is essential for adequate management of the condition until delivery can occur.
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spelling pubmed-86104852021-11-29 Pheochromocytoma Leading to Multiorgan Failure in a Pregnant Patient: A Case Report Myatt, Toby Barker, Margot Clin Pract Cases Emerg Med Case Report INTRODUCTION: Pheochromocytoma, a neuroendocrine tumor that secretes catecholamines, can present with episodic sweating, diaphoresis, headaches, and hypertension, as well as cardiac and pulmonary involvement. In a pregnant patient, it must be differentiated from preeclampsia, a leading cause of maternal mortality in the developed world, which can similarly present with hypertension and multiorgan involvement. Both conditions require early diagnosis and treatment to reduce maternal and fetal morbidity and mortality. CASE REPORT: We discuss the case of a pregnant patient at approximately 24 weeks’ gestation presenting with chest pain and shortness of breath who was found to have a left adrenal mass and hypertensive urgency. The patient acutely decompensated during the course of evaluation. She ultimately suffered pregnancy loss and multiorgan failure requiring percutaneous heart pump placement and extracorporeal membrane oxygenation therapy for support before fully recovering. The adrenal mass was confirmed to be a pheochromocytoma after excision and contributed to the development of hypertensive emergency with multiorgan failure. CONCLUSION: Pheochromocytoma during pregnancy is a rare condition but must remain on the differential until ruled out to improve patient outcomes as much as possible. Obtaining blood pressure control is imperative to reducing maternal and fetal mortality. Preeclampsia is similarly serious, and early diagnosis is essential for adequate management of the condition until delivery can occur. University of California Irvine, Department of Emergency Medicine publishing Western Journal of Emergency Medicine 2021-08-31 /pmc/articles/PMC8610485/ /pubmed/34813427 http://dx.doi.org/10.5811/cpcem.2021.6.52727 Text en Copyright: © 2021 Myatt. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) License. See: http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/)
spellingShingle Case Report
Myatt, Toby
Barker, Margot
Pheochromocytoma Leading to Multiorgan Failure in a Pregnant Patient: A Case Report
title Pheochromocytoma Leading to Multiorgan Failure in a Pregnant Patient: A Case Report
title_full Pheochromocytoma Leading to Multiorgan Failure in a Pregnant Patient: A Case Report
title_fullStr Pheochromocytoma Leading to Multiorgan Failure in a Pregnant Patient: A Case Report
title_full_unstemmed Pheochromocytoma Leading to Multiorgan Failure in a Pregnant Patient: A Case Report
title_short Pheochromocytoma Leading to Multiorgan Failure in a Pregnant Patient: A Case Report
title_sort pheochromocytoma leading to multiorgan failure in a pregnant patient: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610485/
https://www.ncbi.nlm.nih.gov/pubmed/34813427
http://dx.doi.org/10.5811/cpcem.2021.6.52727
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