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Protein kinase Cδ is essential for the IgG response against T-cell-independent type 2 antigens and commensal bacteria

Antigens (Ags) with multivalent and repetitive structure elicit IgG production in a T-cell-independent manner. However, the mechanisms by which such T-cell-independent type-2 (TI-2) Ags induce IgG responses remain obscure. Here, we report that B-cell receptor (BCR) engagement with a TI-2 Ag but not...

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Detalles Bibliográficos
Autores principales:	Fukao, Saori, Haniuda, Kei, Tamaki, Hiromasa, Kitamura, Daisuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610492/ https://www.ncbi.nlm.nih.gov/pubmed/34693907 http://dx.doi.org/10.7554/eLife.72116

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