Semi-continuous Propagation of Influenza A Virus and Its Defective Interfering Particles: Analyzing the Dynamic Competition To Select Candidates for Antiviral Therapy

Defective interfering particles (DIPs) of influenza A virus (IAV) are naturally occurring mutants that have an internal deletion in one of their eight viral RNA (vRNA) segments, rendering them propagation-incompetent. Upon coinfection with infectious standard virus (STV), DIPs interfere with STV rep...

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Detalles Bibliográficos
Autores principales: Pelz, Lars, Rüdiger, Daniel, Dogra, Tanya, Alnaji, Fadi G., Genzel, Yvonne, Brooke, Christopher B., Kupke, Sascha Y., Reichl, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Genetic Diversity and Evolution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610589/
https://www.ncbi.nlm.nih.gov/pubmed/34550771
http://dx.doi.org/10.1128/JVI.01174-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610589/
https://www.ncbi.nlm.nih.gov/pubmed/34550771
http://dx.doi.org/10.1128/JVI.01174-21

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