Cargando…

Semi-continuous Propagation of Influenza A Virus and Its Defective Interfering Particles: Analyzing the Dynamic Competition To Select Candidates for Antiviral Therapy

Defective interfering particles (DIPs) of influenza A virus (IAV) are naturally occurring mutants that have an internal deletion in one of their eight viral RNA (vRNA) segments, rendering them propagation-incompetent. Upon coinfection with infectious standard virus (STV), DIPs interfere with STV rep...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pelz, Lars, Rüdiger, Daniel, Dogra, Tanya, Alnaji, Fadi G., Genzel, Yvonne, Brooke, Christopher B., Kupke, Sascha Y., Reichl, Udo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Genetic Diversity and Evolution
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610589/ https://www.ncbi.nlm.nih.gov/pubmed/34550771 http://dx.doi.org/10.1128/JVI.01174-21

Ejemplares similares

A Novel Type of Influenza A Virus-Derived Defective Interfering Particle with Nucleotide Substitutions in Its Genome
por: Kupke, Sascha Young, et al.
Publicado: (2019)

Multiscale model of defective interfering particle replication for influenza A virus infection in animal cell culture
por: Rüdiger, Daniel, et al.
Publicado: (2021)

Generation of “OP7 chimera” defective interfering influenza A particle preparations free of infectious virus that show antiviral efficacy in mice
por: Dogra, Tanya, et al.
Publicado: (2023)

Cell culture–based production of defective interfering influenza A virus particles in perfusion mode using an alternating tangential flow filtration system
por: Hein, Marc D., et al.
Publicado: (2021)

Unique Evolution of Antiviral Tetherin in Bats
por: Hayward, Joshua A., et al.
Publicado: (2022)

Broad-Spectrum Antiviral Activity of Influenza A Defective Interfering Particles against Respiratory Syncytial, Yellow Fever, and Zika Virus Replication In Vitro
por: Pelz, Lars, et al.
Publicado: (2023)

OP7, a novel influenza A virus defective interfering particle: production, purification, and animal experiments demonstrating antiviral potential
por: Hein, Marc D., et al.
Publicado: (2020)

Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles
por: Hein, Marc D., et al.
Publicado: (2021)

Cell culture-based production of defective interfering particles for influenza antiviral therapy
por: Wasik, Milena A., et al.
Publicado: (2017)

Influenza virus DI particles: Defective interfering or delightfully interesting?
por: Alnaji, Fadi G., et al.
Publicado: (2020)

Unfixed Endogenous Retroviral Insertions in the Human Population
por: Marchi, Emanuele, et al.
Publicado: (2014)

Deep Sequencing of Norovirus Genomes Defines Evolutionary Patterns in an Urban Tropical Setting
por: Cotten, Matthew, et al.
Publicado: (2014)

Powerful Sequence Similarity Search Methods and In-Depth Manual Analyses Can Identify Remote Homologs in Many Apparently “Orphan” Viral Proteins
por: Kuchibhatla, Durga B., et al.
Publicado: (2014)

Stability of the Parainfluenza Virus 5 Genome Revealed by Deep Sequencing of Strains Isolated from Different Hosts and following Passage in Cell Culture
por: Rima, Bert K., et al.
Publicado: (2014)

Genome Diversity of Epstein-Barr Virus from Multiple Tumor Types and Normal Infection
por: Palser, Anne L., et al.
Publicado: (2015)

Local Evolutionary Patterns of Human Respiratory Syncytial Virus Derived from Whole-Genome Sequencing
por: Agoti, Charles N., et al.
Publicado: (2015)

Phylodynamics of Enterovirus A71-Associated Hand, Foot, and Mouth Disease in Viet Nam
por: Geoghegan, Jemma L., et al.
Publicado: (2015)

Sinorhizobium meliloti Phage ΦM9 Defines a New Group of T4 Superfamily Phages with Unusual Genomic Features but a Common T=16 Capsid
por: Johnson, Matthew C., et al.
Publicado: (2015)

Novel Denisovan and Neanderthal Retroviruses
por: Lee, Adam, et al.
Publicado: (2014)

Accumulation of Human-Adapting Mutations during Circulation of A(H1N1)pdm09 Influenza Virus in Humans in the United Kingdom
por: Elderfield, Ruth A., et al.
Publicado: (2014)

Evolution of Cocirculating Varicella-Zoster Virus Genotypes during a Chickenpox Outbreak in Guinea-Bissau
por: Depledge, Daniel P., et al.
Publicado: (2014)

Molecular Evolutionary Dynamics of Respiratory Syncytial Virus Group A in Recurrent Epidemics in Coastal Kenya
por: Otieno, James R., et al.
Publicado: (2016)

Increasing Clinical Severity during a Dengue Virus Type 3 Cuban Epidemic: Deep Sequencing of Evolving Viral Populations
por: Rodriguez-Roche, Rosmari, et al.
Publicado: (2016)

Genetic Stability of Bacterial Artificial Chromosome-Derived Human Cytomegalovirus during Culture In Vitro
por: Murrell, Isa, et al.
Publicado: (2016)

Salmon Gill Poxvirus, the Deepest Representative of the Chordopoxvirinae
por: Gjessing, Mona C., et al.
Publicado: (2015)

Molecular Epidemiology and Evolution of Influenza Viruses Circulating within European Swine between 2009 and 2013
por: Watson, Simon J., et al.
Publicado: (2015)

Single-Genome Sequencing of Hepatitis C Virus in Donor-Recipient Pairs Distinguishes Modes and Models of Virus Transmission and Early Diversification
por: Li, Hui, et al.
Publicado: (2015)

Genetics, Receptor Binding, Replication, and Mammalian Transmission of H4 Avian Influenza Viruses Isolated from Live Poultry Markets in China
por: Liang, Libin, et al.
Publicado: (2016)

Spatial-Temporal Patterns of Viral Amplification and Interference Initiated by a Single Infected Cell
por: Akpinar, Fulya, et al.
Publicado: (2016)

Characterizing the Diverse Mutational Pathways Associated with R5-Tropic Maraviroc Resistance: HIV-1 That Uses the Drug-Bound CCR5 Coreceptor
por: Jiang, Xiaowei, et al.
Publicado: (2015)

Successive Respiratory Syncytial Virus Epidemics in Local Populations Arise from Multiple Variant Introductions, Providing Insights into Virus Persistence
por: Agoti, Charles N., et al.
Publicado: (2015)

Characterization of a Novel Hepadnavirus in the White Sucker (Catostomus commersonii) from the Great Lakes Region of the United States
por: Hahn, Cassidy M., et al.
Publicado: (2015)

Ecuador Paraiso Escondido Virus, a New Flavivirus Isolated from New World Sand Flies in Ecuador, Is the First Representative of a Novel Clade in the Genus Flavivirus
por: Alkan, Cigdem, et al.
Publicado: (2015)

Complete Unique Genome Sequence, Expression Profile, and Salivary Gland Tissue Tropism of the Herpesvirus 7 Homolog in Pigtailed Macaques
por: Staheli, Jeannette P., et al.
Publicado: (2016)

Time-Dependent Rate Phenomenon in Viruses
por: Aiewsakun, Pakorn, et al.
Publicado: (2016)

Deep Sequencing of Influenza A Virus from a Human Challenge Study Reveals a Selective Bottleneck and Only Limited Intrahost Genetic Diversification
por: Sobel Leonard, Ashley, et al.
Publicado: (2016)

Evidence for the Introduction, Reassortment, and Persistence of Diverse Influenza A Viruses in Antarctica
por: Hurt, Aeron C., et al.
Publicado: (2016)

Characterization of Clade 7.2 H5 Avian Influenza Viruses That Continue To Circulate in Chickens in China
por: Liu, Liling, et al.
Publicado: (2016)

Characterization of Equine Infectious Anemia Virus Long Terminal Repeat Quasispecies In Vitro and In Vivo
por: Wang, Xue-Feng, et al.
Publicado: (2018)

Weaker HLA Footprints on HIV in the Unique and Highly Genetically Admixed Host Population of Mexico
por: Soto-Nava, Maribel, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_bvhm8igdggql4237v7con7jvk6