Cargando…
Aberrant Fluid Shear Stress Contributes to Articular Cartilage Pathogenesis via Epigenetic Regulation of ZBTB20 by H3K4me3
PURPOSE: Osteoarthritis (OA) is a common disease for human beings, characterized by severe inflammation, cartilage degradation, and subchondral bone destruction. However, current therapies are limited to relieving pain or joint replacement and no effective treatment methods have been discovered to i...
Autores principales: | Jin, Yu, Li, Zhenxia, Wu, Yanran, Li, Hairui, Liu, Zhen, Liu, Lu, Ouyang, Ningjuan, Zhou, Ting, Fang, Bing, Xia, Lunguo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610757/ https://www.ncbi.nlm.nih.gov/pubmed/34824542 http://dx.doi.org/10.2147/JIR.S339382 |
Ejemplares similares
-
Histone demethylase JMJD3 downregulation protects against aberrant force-induced osteoarthritis through epigenetic control of NR4A1
por: Jin, Yu, et al.
Publicado: (2022) -
Aberrant Calreticulin Expression in Articular Cartilage of Dio2 Deficient Mice
por: Bomer, Nils, et al.
Publicado: (2016) -
Chromatin accessibility landscape of articular knee cartilage reveals aberrant enhancer regulation in osteoarthritis
por: Liu, Ye, et al.
Publicado: (2018) -
Teriparatide ameliorates articular cartilage degradation and aberrant subchondral bone remodeling in DMM mice
por: Li, Guoqing, et al.
Publicado: (2022) -
Articular cartilage and changes in Arthritis: Collagen of articular cartilage
por: Eyre, David
Publicado: (2002)