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Brunner’s gland hyperplasia associated with lipomatous pseudohypertrophy of the pancreas presenting with gastrointestinal bleeding: A case report
BACKGROUND: Brunner’s gland hyperplasia (BGH) is a rare benign lesion of the duodenum. Lipomatous pseudohypertrophy (LiPH) of the pancreas is an extremely rare disease. Because each condition is rare, the probability of purely coincidental coexistence of both conditions is extremely low. CASE SUMMAR...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Baishideng Publishing Group Inc
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610885/ https://www.ncbi.nlm.nih.gov/pubmed/34877305 http://dx.doi.org/10.12998/wjcc.v9.i31.9670 |
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author | Nguyen, Long Cong Vu, Khanh Truong Vo, Trang Thi Thuy Trinh, Chau Ha Do, Tan Dang Pham, Ngoc Thi Van Pham, Tuyen Van Nguyen, Thanh Tuan Nguyen, Hiep Canh Byeon, Jeong-Sik |
author_facet | Nguyen, Long Cong Vu, Khanh Truong Vo, Trang Thi Thuy Trinh, Chau Ha Do, Tan Dang Pham, Ngoc Thi Van Pham, Tuyen Van Nguyen, Thanh Tuan Nguyen, Hiep Canh Byeon, Jeong-Sik |
author_sort | Nguyen, Long Cong |
collection | PubMed |
description | BACKGROUND: Brunner’s gland hyperplasia (BGH) is a rare benign lesion of the duodenum. Lipomatous pseudohypertrophy (LiPH) of the pancreas is an extremely rare disease. Because each condition is rare, the probability of purely coincidental coexistence of both conditions is extremely low. CASE SUMMARY: We report a 26-year-old man presenting to our hospital with symptoms of recurrent upper gastrointestinal bleeding. Upper gastrointestinal endoscopy showed a huge pedunculated polypoid lesion in the duodenum with bleeding at the base of the lesion. Histopathological examination of the duodenal biopsy specimens showed BGH. Besides, abdominal computed tomography and magnetic resonance imaging revealed marked fat replacement over the entire pancreas, confirmed by histopathological evaluation on percutaneous pancreatic biopsies. Based on the radiological and histological findings, LiPH of the pancreas and BGH were diagnosed. The patient refused any surgical intervention. Therefore, he was managed with supportive treatment. The patient’s symptoms improved and there was no further bleeding. CONCLUSION: This is the first well-documented case showing the coexistence of LiPH of the pancreas and BGH. |
format | Online Article Text |
id | pubmed-8610885 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-86108852021-12-06 Brunner’s gland hyperplasia associated with lipomatous pseudohypertrophy of the pancreas presenting with gastrointestinal bleeding: A case report Nguyen, Long Cong Vu, Khanh Truong Vo, Trang Thi Thuy Trinh, Chau Ha Do, Tan Dang Pham, Ngoc Thi Van Pham, Tuyen Van Nguyen, Thanh Tuan Nguyen, Hiep Canh Byeon, Jeong-Sik World J Clin Cases Case Report BACKGROUND: Brunner’s gland hyperplasia (BGH) is a rare benign lesion of the duodenum. Lipomatous pseudohypertrophy (LiPH) of the pancreas is an extremely rare disease. Because each condition is rare, the probability of purely coincidental coexistence of both conditions is extremely low. CASE SUMMARY: We report a 26-year-old man presenting to our hospital with symptoms of recurrent upper gastrointestinal bleeding. Upper gastrointestinal endoscopy showed a huge pedunculated polypoid lesion in the duodenum with bleeding at the base of the lesion. Histopathological examination of the duodenal biopsy specimens showed BGH. Besides, abdominal computed tomography and magnetic resonance imaging revealed marked fat replacement over the entire pancreas, confirmed by histopathological evaluation on percutaneous pancreatic biopsies. Based on the radiological and histological findings, LiPH of the pancreas and BGH were diagnosed. The patient refused any surgical intervention. Therefore, he was managed with supportive treatment. The patient’s symptoms improved and there was no further bleeding. CONCLUSION: This is the first well-documented case showing the coexistence of LiPH of the pancreas and BGH. Baishideng Publishing Group Inc 2021-11-06 2021-11-06 /pmc/articles/PMC8610885/ /pubmed/34877305 http://dx.doi.org/10.12998/wjcc.v9.i31.9670 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
spellingShingle | Case Report Nguyen, Long Cong Vu, Khanh Truong Vo, Trang Thi Thuy Trinh, Chau Ha Do, Tan Dang Pham, Ngoc Thi Van Pham, Tuyen Van Nguyen, Thanh Tuan Nguyen, Hiep Canh Byeon, Jeong-Sik Brunner’s gland hyperplasia associated with lipomatous pseudohypertrophy of the pancreas presenting with gastrointestinal bleeding: A case report |
title | Brunner’s gland hyperplasia associated with lipomatous pseudohypertrophy of the pancreas presenting with gastrointestinal bleeding: A case report |
title_full | Brunner’s gland hyperplasia associated with lipomatous pseudohypertrophy of the pancreas presenting with gastrointestinal bleeding: A case report |
title_fullStr | Brunner’s gland hyperplasia associated with lipomatous pseudohypertrophy of the pancreas presenting with gastrointestinal bleeding: A case report |
title_full_unstemmed | Brunner’s gland hyperplasia associated with lipomatous pseudohypertrophy of the pancreas presenting with gastrointestinal bleeding: A case report |
title_short | Brunner’s gland hyperplasia associated with lipomatous pseudohypertrophy of the pancreas presenting with gastrointestinal bleeding: A case report |
title_sort | brunner’s gland hyperplasia associated with lipomatous pseudohypertrophy of the pancreas presenting with gastrointestinal bleeding: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610885/ https://www.ncbi.nlm.nih.gov/pubmed/34877305 http://dx.doi.org/10.12998/wjcc.v9.i31.9670 |
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