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ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury
Angiotensin-converting enzyme 2 (ACE2) is a receptor for cell entry of SARS-CoV-2, and recombinant soluble ACE2 protein inhibits SARS-CoV-2 infection as a decoy. ACE2 is a carboxypeptidase that degrades angiotensin II, thereby improving the pathologies of cardiovascular disease or acute lung injury....
Autores principales: | Yamaguchi, Tomokazu, Hoshizaki, Midori, Minato, Takafumi, Nirasawa, Satoru, Asaka, Masamitsu N., Niiyama, Mayumi, Imai, Masaki, Uda, Akihiko, Chan, Jasper Fuk-Woo, Takahashi, Saori, An, Jianbo, Saku, Akari, Nukiwa, Ryota, Utsumi, Daichi, Kiso, Maki, Yasuhara, Atsuhiro, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Fujino, Yuji, Motoyama, Satoru, Nagata, Satoshi, Penninger, Josef M., Kamada, Haruhiko, Yuen, Kwok-Yung, Kamitani, Wataru, Maeda, Ken, Kawaoka, Yoshihiro, Yasutomi, Yasuhiro, Imai, Yumiko, Kuba, Keiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610983/ https://www.ncbi.nlm.nih.gov/pubmed/34815389 http://dx.doi.org/10.1038/s41467-021-27097-8 |
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