Apelin-13 in septic shock: effective in supporting hemodynamics in sheep but compromised by enzymatic breakdown in patients

Sepsis is a prevalent life-threatening condition related to a systemic infection, and with unresolved issues including refractory septic shock and organ failures. Endogenously released catecholamines are often inefficient to maintain blood pressure, and low reactivity to exogenous catecholamines wit...

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Detalles Bibliográficos
Autores principales: Coquerel, David, Lamoureux, Julie, Chagnon, Frédéric, Trân, Kien, Sage, Michael, Fortin-Pellerin, Etienne, Delile, Eugénie, Sainsily, Xavier, Fournier, Justin, Dumont, Audrey-Ann, Auger-Messier, Mannix, Sarret, Philippe, Marsault, Eric, Praud, Jean-Paul, Fülöp, Tamàs, Lesur, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611018/
https://www.ncbi.nlm.nih.gov/pubmed/34815457
http://dx.doi.org/10.1038/s41598-021-02087-4

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