A 3D primary human cell-based in vitro model of non-alcoholic steatohepatitis for efficacy testing of clinical drug candidates

Non-alcoholic steatohepatitis (NASH) is a progressive and severe liver disease, characterized by lipid accumulation, inflammation, and downstream fibrosis. Despite its increasing prevalence, there is no approved treatment yet available for patients. This has been at least partially due to the lack o...

Descripción completa

Detalles Bibliográficos
Autores principales: Ströbel, Simon, Kostadinova, Radina, Fiaschetti-Egli, Katia, Rupp, Jana, Bieri, Manuela, Pawlowska, Agnieszka, Busler, Donna, Hofstetter, Thomas, Sanchez, Katarzyna, Grepper, Sue, Thoma, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611054/
https://www.ncbi.nlm.nih.gov/pubmed/34815444
http://dx.doi.org/10.1038/s41598-021-01951-7

Ejemplares similares

Ejemplares similares