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Potential molecular link between the β-amyloid precursor protein (APP) and hypoxanthine-guanine phosphoribosyltransferase (HGprt) enzyme in Lesch-Nyhan disease and cancer

Lesch-Nyhan disease (LND) is a rare X-linked inherited neurogenetic disorders of purine metabolic in which the cytoplasmic enzyme, hypoxanthine-guanine phosphoribosyltransferase (HGprt) is defective. Despite having been characterized over 60 years ago, however, up to now, there is no satisfactory ex...

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Detalles Bibliográficos
Autor principal:	Nguyen, Khue Vu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AIMS Press 2021
Materias:	Mini Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611187/ https://www.ncbi.nlm.nih.gov/pubmed/34877405 http://dx.doi.org/10.3934/Neuroscience.2021030

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