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Ventrolateral ventromedial hypothalamic nucleus GABA neuron adaptation to recurring Hypoglycemia correlates with up-regulated 5′-AMP-activated protein kinase activity

Gamma-aminobutyric acid (GABA) acts on ventromedial hypothalamic targets to suppress counter-regulatory hormone release, thereby lowering blood glucose. Maladaptive up-regulation of GABA signaling is implicated in impaired counter-regulatory outflow during recurring insulin-induced hypoglycemia (RII...

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Detalles Bibliográficos
Autores principales: Alhamyani, Abdulrahman, Napit, Prabhat R, Ali, Haider, Ibrahim, Mostafa MH, Briski, Karen P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIMS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611193/
https://www.ncbi.nlm.nih.gov/pubmed/34877402
http://dx.doi.org/10.3934/Neuroscience.2021027