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Hypoxic Pretreatment of Adipose-Derived Stem Cells Accelerates Diabetic Wound Healing via circ-Gcap14 and HIF-1α/VEGF Mediated Angiopoiesis

BACKGROUND AND OBJECTIVES: Adipose-derived stem cell (ADSC) transplantation improves stem cell paracrine function and can enhance wound healing. However, in diabetic patients, glucose-associated effects on this function and cell survival lead to impaired wound closure, thereby limiting ADSC transpla...

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Detalles Bibliográficos
Autores principales: Wang, Zhi, Feng, Cheng, Liu, Hao, Meng, Tian, Huang, Weiqing, Long, Xiao, Wang, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Stem Cell Research 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611313/
https://www.ncbi.nlm.nih.gov/pubmed/34456191
http://dx.doi.org/10.15283/ijsc21050