Alzheimer's disease: Newer biomarkers

Fifty million people are affected with dementia worldwide with Alzheimer's disease (AD) accounting for 70%–80% of these cases. In India alone, 4.1 million people suffered from dementia in 2015. To date, there are no definitive treatment options for AD and the overall treatment gap in India stan...

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Autores principales: Dangi, Ankit, Chatterjee, Kaushik, Banwa, Manjur Shah, Chauhan, Vinay Singh, Yadav, Prateek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Contemporary Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611557/
https://www.ncbi.nlm.nih.gov/pubmed/34908720
http://dx.doi.org/10.4103/0972-6748.328840
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author Dangi, Ankit
Chatterjee, Kaushik
Banwa, Manjur Shah
Chauhan, Vinay Singh
Yadav, Prateek
author_facet Dangi, Ankit
Chatterjee, Kaushik
Banwa, Manjur Shah
Chauhan, Vinay Singh
Yadav, Prateek
author_sort Dangi, Ankit
collection PubMed
description Fifty million people are affected with dementia worldwide with Alzheimer's disease (AD) accounting for 70%–80% of these cases. In India alone, 4.1 million people suffered from dementia in 2015. To date, there are no definitive treatment options for AD and the overall treatment gap in India stands at 90%. Attempts have been made to define AD biologically. This has been made possible due to advances in the identification of biomarkers that indicate the neuropathological changes responsible for AD. Identification of these biomarkers has implications for disease staging, prognostication, and identifying drug targets. Here, we summarize the advances in the field of biomarkers in AD.
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spelling pubmed-86115572021-12-13 Alzheimer's disease: Newer biomarkers Dangi, Ankit Chatterjee, Kaushik Banwa, Manjur Shah Chauhan, Vinay Singh Yadav, Prateek Ind Psychiatry J Contemporary Issue Fifty million people are affected with dementia worldwide with Alzheimer's disease (AD) accounting for 70%–80% of these cases. In India alone, 4.1 million people suffered from dementia in 2015. To date, there are no definitive treatment options for AD and the overall treatment gap in India stands at 90%. Attempts have been made to define AD biologically. This has been made possible due to advances in the identification of biomarkers that indicate the neuropathological changes responsible for AD. Identification of these biomarkers has implications for disease staging, prognostication, and identifying drug targets. Here, we summarize the advances in the field of biomarkers in AD. Wolters Kluwer - Medknow 2021-10 2021-10-22 /pmc/articles/PMC8611557/ /pubmed/34908720 http://dx.doi.org/10.4103/0972-6748.328840 Text en Copyright: © 2021 Industrial Psychiatry Journal https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Contemporary Issue
Dangi, Ankit
Chatterjee, Kaushik
Banwa, Manjur Shah
Chauhan, Vinay Singh
Yadav, Prateek
Alzheimer's disease: Newer biomarkers
title Alzheimer's disease: Newer biomarkers
title_full Alzheimer's disease: Newer biomarkers
title_fullStr Alzheimer's disease: Newer biomarkers
title_full_unstemmed Alzheimer's disease: Newer biomarkers
title_short Alzheimer's disease: Newer biomarkers
title_sort alzheimer's disease: newer biomarkers
topic Contemporary Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611557/
https://www.ncbi.nlm.nih.gov/pubmed/34908720
http://dx.doi.org/10.4103/0972-6748.328840
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AT chauhanvinaysingh alzheimersdiseasenewerbiomarkers
AT yadavprateek alzheimersdiseasenewerbiomarkers

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