Hyperphosphorylation of Tau Due to the Interference of Protein Phosphatase Methylesterase-1 Overexpression by MiR-125b-5p in Melatonin Receptor Knockout Mice

Melatonin has been indicated to ameliorate tau hyperphosphorylation in the pathogenesis of tau diseases, but the role of melatonin-receptor signal transduction has not been clearly discovered. In this study, we found intensive tau hyperphosphorylation in melatonin receptor knockout mice. Bielschowsk...

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Detalles Bibliográficos
Autores principales: Zhao, Han, Feng, Lingyan, Zhong, Wei, Zhen, Hongyan, Chi, Qingjia, Wang, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611649/
https://www.ncbi.nlm.nih.gov/pubmed/34769281
http://dx.doi.org/10.3390/ijms222111850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611649/
https://www.ncbi.nlm.nih.gov/pubmed/34769281
http://dx.doi.org/10.3390/ijms222111850

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