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Hyperphosphorylation of Tau Due to the Interference of Protein Phosphatase Methylesterase-1 Overexpression by MiR-125b-5p in Melatonin Receptor Knockout Mice
Melatonin has been indicated to ameliorate tau hyperphosphorylation in the pathogenesis of tau diseases, but the role of melatonin-receptor signal transduction has not been clearly discovered. In this study, we found intensive tau hyperphosphorylation in melatonin receptor knockout mice. Bielschowsk...
Autores principales: | Zhao, Han, Feng, Lingyan, Zhong, Wei, Zhen, Hongyan, Chi, Qingjia, Wang, Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611649/ https://www.ncbi.nlm.nih.gov/pubmed/34769281 http://dx.doi.org/10.3390/ijms222111850 |
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