Can repurposing drugs play a role in malaria control?

Innovative drug treatments for malaria, optimally with novel targets, are needed to combat the threat of parasite drug resistance. As drug development efforts continue, there may be a role for a host-targeting, repurposed cancer drug administered together with an artemisinin combination therapy that...

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Detalles Bibliográficos
Autores principales: Cooper, Roland A., Kirkman, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Viewpoint
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611732/
https://www.ncbi.nlm.nih.gov/pubmed/34807244
http://dx.doi.org/10.1084/jem.20211512
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author Cooper, Roland A.
Kirkman, Laura
author_facet Cooper, Roland A.
Kirkman, Laura
author_sort Cooper, Roland A.
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description Innovative drug treatments for malaria, optimally with novel targets, are needed to combat the threat of parasite drug resistance. As drug development efforts continue, there may be a role for a host-targeting, repurposed cancer drug administered together with an artemisinin combination therapy that was shown to improve the speed of recovery from a malaria infection.
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spelling pubmed-86117322022-06-06 Can repurposing drugs play a role in malaria control? Cooper, Roland A. Kirkman, Laura J Exp Med Viewpoint Innovative drug treatments for malaria, optimally with novel targets, are needed to combat the threat of parasite drug resistance. As drug development efforts continue, there may be a role for a host-targeting, repurposed cancer drug administered together with an artemisinin combination therapy that was shown to improve the speed of recovery from a malaria infection. Rockefeller University Press 2021-11-22 /pmc/articles/PMC8611732/ /pubmed/34807244 http://dx.doi.org/10.1084/jem.20211512 Text en © 2021 Cooper and Kirkman https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Viewpoint
Cooper, Roland A.
Kirkman, Laura
Can repurposing drugs play a role in malaria control?
title Can repurposing drugs play a role in malaria control?
title_full Can repurposing drugs play a role in malaria control?
title_fullStr Can repurposing drugs play a role in malaria control?
title_full_unstemmed Can repurposing drugs play a role in malaria control?
title_short Can repurposing drugs play a role in malaria control?
title_sort can repurposing drugs play a role in malaria control?
topic Viewpoint
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611732/
https://www.ncbi.nlm.nih.gov/pubmed/34807244
http://dx.doi.org/10.1084/jem.20211512
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