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Disruption of rack1 suppresses SHH‐type medulloblastoma formation in mice
INTRODUCTION: Medulloblastoma (MB) is a malignant pediatric brain tumor that arises in the cerebellar granular neurons. Sonic Hedgehog subtype of MB (SHH‐MB) is one of the major subtypes of MB in the clinic. However, the molecular mechanisms underlying MB tumorigenesis are still not fully understood...
Autores principales: | Liu, Fengjiao, Shao, Jingyuan, Yang, Haihong, Yang, Guochao, Zhu, Qian, Wu, Yan, Zhu, Lingling, Wu, Haitao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611787/ https://www.ncbi.nlm.nih.gov/pubmed/34480519 http://dx.doi.org/10.1111/cns.13728 |
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