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Disruption of rack1 suppresses SHH‐type medulloblastoma formation in mice

INTRODUCTION: Medulloblastoma (MB) is a malignant pediatric brain tumor that arises in the cerebellar granular neurons. Sonic Hedgehog subtype of MB (SHH‐MB) is one of the major subtypes of MB in the clinic. However, the molecular mechanisms underlying MB tumorigenesis are still not fully understood...

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Detalles Bibliográficos
Autores principales: Liu, Fengjiao, Shao, Jingyuan, Yang, Haihong, Yang, Guochao, Zhu, Qian, Wu, Yan, Zhu, Lingling, Wu, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611787/
https://www.ncbi.nlm.nih.gov/pubmed/34480519
http://dx.doi.org/10.1111/cns.13728

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