Cargando…
A novel equivalence probability weighted power prior for using historical control data in an adaptive clinical trial design: A comparison to standard methods
A standard two‐arm randomised controlled trial usually compares an intervention to a control treatment with equal numbers of patients randomised to each treatment arm and only data from within the current trial are used to assess the treatment effect. Historical data are used when designing new tria...
Autores principales: | Bennett, Maxine, White, Simon, Best, Nicky, Mander, Adrian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611797/ https://www.ncbi.nlm.nih.gov/pubmed/33474798 http://dx.doi.org/10.1002/pst.2088 |
Ejemplares similares
-
Incorporating historical controls in clinical trials with longitudinal outcomes using the modified power prior
por: Qi, Hongchao, et al.
Publicado: (2022) -
An optimal stratified Simon two‐stage design
por: Parashar, Deepak, et al.
Publicado: (2016) -
Assessing efficacy in important subgroups in confirmatory trials: An example using Bayesian dynamic borrowing
por: Best, Nicky, et al.
Publicado: (2021) -
Escalation strategies for combination therapy Phase I trials
por: Sweeting, Michael J, et al.
Publicado: (2012) -
Do single‐arm trials have a role in drug development plans incorporating randomised trials?
por: Grayling, Michael J., et al.
Publicado: (2015)