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Aloin induced apoptosis by enhancing autophagic flux through the PI3K/AKT axis in osteosarcoma

BACKGROUND: Osteosarcoma is a malignant tumor of bone and soft tissue in adolescents. Due to its tumor biological behavior pattern, osteosarcoma usually generates poor prognosis. Autophagy is an important self-defense mechanism in osteosarcoma. METHODS: Cell viability in IC(50) testing and reverse a...

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Detalles Bibliográficos
Autores principales:	He, Jiaming, Zhang, Wenkan, Zhou, Xiaozhong, Yan, Weiqi, Wang, Zhan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611986/ https://www.ncbi.nlm.nih.gov/pubmed/34819120 http://dx.doi.org/10.1186/s13020-021-00520-4

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