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Peri-Operative Glycemic Dynamics in a Chinese Patient With Type 2 Diabetes Undergoing Laparoscopic Sleeve Gastrectomy

Obesity and type 2 diabetes (T2D) are prevalent issues in China. Bariatric and metabolic surgery, by reducing the size of the stomach through the removal of a portion of the stomach using laparoscopy (laparoscopic sleeve gastrectomy (LSG)), induces the remarkable remission of T2D inpatients. Plasma...

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Autores principales: Wen, Song, Gong, Min, Zhou, Ligang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612065/
https://www.ncbi.nlm.nih.gov/pubmed/34824939
http://dx.doi.org/10.7759/cureus.19029
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author Wen, Song
Gong, Min
Zhou, Ligang
author_facet Wen, Song
Gong, Min
Zhou, Ligang
author_sort Wen, Song
collection PubMed
description Obesity and type 2 diabetes (T2D) are prevalent issues in China. Bariatric and metabolic surgery, by reducing the size of the stomach through the removal of a portion of the stomach using laparoscopy (laparoscopic sleeve gastrectomy (LSG)), induces the remarkable remission of T2D inpatients. Plasma glucose (PG) was reported to be at a lower than normal level in Caucasian patients a few weeks after surgery, which is not well-documented in Chinese patients who have a lower body mass index (BMI) compared to Caucasians. Thus, we adopted the use of a continuous glucose monitoring system (CGMS) in a Chinese patient to monitor postoperative glucose levels. We found that the level of PG lowered to the normal range four days after LSG surgery while weight loss was not significantly reduced. It is indicated that the main mechanism of LSG inducing remission of T2DM is the limitation of food intake in addition to the imbalance of a few gastrointestinal hormones such as glucagon-like peptide 1 (GLP-1), Ghrelin. The lower the BMI, the lower the adipose tissue, and the faster the decrease in PG after bariatric and metabolic surgery.
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spelling pubmed-86120652021-11-24 Peri-Operative Glycemic Dynamics in a Chinese Patient With Type 2 Diabetes Undergoing Laparoscopic Sleeve Gastrectomy Wen, Song Gong, Min Zhou, Ligang Cureus Endocrinology/Diabetes/Metabolism Obesity and type 2 diabetes (T2D) are prevalent issues in China. Bariatric and metabolic surgery, by reducing the size of the stomach through the removal of a portion of the stomach using laparoscopy (laparoscopic sleeve gastrectomy (LSG)), induces the remarkable remission of T2D inpatients. Plasma glucose (PG) was reported to be at a lower than normal level in Caucasian patients a few weeks after surgery, which is not well-documented in Chinese patients who have a lower body mass index (BMI) compared to Caucasians. Thus, we adopted the use of a continuous glucose monitoring system (CGMS) in a Chinese patient to monitor postoperative glucose levels. We found that the level of PG lowered to the normal range four days after LSG surgery while weight loss was not significantly reduced. It is indicated that the main mechanism of LSG inducing remission of T2DM is the limitation of food intake in addition to the imbalance of a few gastrointestinal hormones such as glucagon-like peptide 1 (GLP-1), Ghrelin. The lower the BMI, the lower the adipose tissue, and the faster the decrease in PG after bariatric and metabolic surgery. Cureus 2021-10-25 /pmc/articles/PMC8612065/ /pubmed/34824939 http://dx.doi.org/10.7759/cureus.19029 Text en Copyright © 2021, Wen et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Wen, Song
Gong, Min
Zhou, Ligang
Peri-Operative Glycemic Dynamics in a Chinese Patient With Type 2 Diabetes Undergoing Laparoscopic Sleeve Gastrectomy
title Peri-Operative Glycemic Dynamics in a Chinese Patient With Type 2 Diabetes Undergoing Laparoscopic Sleeve Gastrectomy
title_full Peri-Operative Glycemic Dynamics in a Chinese Patient With Type 2 Diabetes Undergoing Laparoscopic Sleeve Gastrectomy
title_fullStr Peri-Operative Glycemic Dynamics in a Chinese Patient With Type 2 Diabetes Undergoing Laparoscopic Sleeve Gastrectomy
title_full_unstemmed Peri-Operative Glycemic Dynamics in a Chinese Patient With Type 2 Diabetes Undergoing Laparoscopic Sleeve Gastrectomy
title_short Peri-Operative Glycemic Dynamics in a Chinese Patient With Type 2 Diabetes Undergoing Laparoscopic Sleeve Gastrectomy
title_sort peri-operative glycemic dynamics in a chinese patient with type 2 diabetes undergoing laparoscopic sleeve gastrectomy
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612065/
https://www.ncbi.nlm.nih.gov/pubmed/34824939
http://dx.doi.org/10.7759/cureus.19029
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