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The cell-surface 5′-nucleotidase CD73 defines a functional T memory cell subset that declines with age
Memory T cells exhibit considerable diversity that determines their ability to be protective. Here, we examine whether changes in T cell heterogeneity contribute to the age-associated failure of immune memory. By screening for age-dependent T cell-surface markers, we identify CD4 and CD8 memory T ce...
Autores principales: | Fang, Fengqin, Cao, Wenqiang, Zhu, Weikang, Lam, Nora, Li, Lingjie, Gaddam, Sadhana, Wang, Yong, Kim, Chulwoo, Lambert, Simon, Zhang, Huimin, Hu, Bin, Farber, Donna L., Weyand, Cornelia M., Goronzy, Jörg J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612175/ https://www.ncbi.nlm.nih.gov/pubmed/34758299 http://dx.doi.org/10.1016/j.celrep.2021.109981 |
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