Cargando…

The cell-surface 5′-nucleotidase CD73 defines a functional T memory cell subset that declines with age

Memory T cells exhibit considerable diversity that determines their ability to be protective. Here, we examine whether changes in T cell heterogeneity contribute to the age-associated failure of immune memory. By screening for age-dependent T cell-surface markers, we identify CD4 and CD8 memory T ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Fang, Fengqin, Cao, Wenqiang, Zhu, Weikang, Lam, Nora, Li, Lingjie, Gaddam, Sadhana, Wang, Yong, Kim, Chulwoo, Lambert, Simon, Zhang, Huimin, Hu, Bin, Farber, Donna L., Weyand, Cornelia M., Goronzy, Jörg J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612175/
https://www.ncbi.nlm.nih.gov/pubmed/34758299
http://dx.doi.org/10.1016/j.celrep.2021.109981

Ejemplares similares