Cargando…

Characterization of Amino Acid Substitutions in the Two-Component Regulatory System AdeRS Identified in Multidrug-Resistant Acinetobacter baumannii

In Acinetobacter baumannii, resistance-nodulation-cell division (RND)-type efflux is a resistance mechanism of great importance since it contributes to reduced susceptibility to multiple antimicrobial compounds. Some mutations within the genes encoding the two-component regulatory system AdeRS appea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lucaßen, K., Xanthopoulou, K., Wille, J., Wille, T., Wen, Y., Hua, X., Seifert, H., Higgins, P. G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612257/ https://www.ncbi.nlm.nih.gov/pubmed/34817237 http://dx.doi.org/10.1128/msphere.00709-21

Ejemplares similares

Resistance to pentamidine is mediated by AdeAB, regulated by AdeRS, and influenced by growth conditions in Acinetobacter baumannii ATCC 17978
por: Adams, Felise G., et al.
Publicado: (2018)

Mechanistic insight into how multidrug resistant Acinetobacter baumannii response regulator AdeR recognizes an intercistronic region
por: Wen, Yurong, et al.
Publicado: (2017)

AdeR-AdeS mutations & overexpression of the AdeABC efflux system in ciprofloxacin-resistant Acinetobacter baumannii clinical isolates
por: Lari, Abdolaziz Rastegar, et al.
Publicado: (2018)

The Acinetobacter baumannii Two-Component System AdeRS Regulates Genes Required for Multidrug Efflux, Biofilm Formation, and Virulence in a Strain-Specific Manner
por: Richmond, Grace E., et al.
Publicado: (2016)

Differential Binding of Carbapenems with the AdeABC Efflux Pump and Modulation of the Expression of AdeB Linked to Novel Mutations within Two-Component System AdeRS in Carbapenem-Resistant Acinetobacter baumannii
por: Roy, Subhasree, et al.
Publicado: (2022)

Proteolysis and multimerization regulate signaling along the two-component regulatory system AdeRS
por: Ouyang, Zhenlin, et al.
Publicado: (2021)

Erratum for Richmond et al., The Acinetobacter baumannii Two-Component System AdeRS Regulates Genes Required for Multidrug Efflux, Biofilm Formation, and Virulence in a Strain-Specific Manner
por: Richmond, Grace E., et al.
Publicado: (2016)

AdeABC Efflux Pump Controlled by AdeRS Two Component System Conferring Resistance to Tigecycline, Omadacycline and Eravacycline in Clinical Carbapenem Resistant Acinetobacter nosocomialis
por: Lee, Yi-Tzu, et al.
Publicado: (2020)

Evaluation of Antibiotic Resistance and adeABC, adeR, adeS Efflux Pump Genes among Foodborne and Clinical Acinetobacter spp. in Türkiye
por: Terkuran, Mevhibe, et al.
Publicado: (2022)

2335. Acinetobacter baumannii Infection—Clinical Profile, Drug Resistance, and Presence of Virulence Factor AdeRS: Experience From a Pediatric Tertiary Care Centre in North India
por: Khurana, Prerna, et al.
Publicado: (2018)

Mobile Genetic Elements Harboring Antibiotic Resistance Determinants in Acinetobacter baumannii Isolates From Bolivia
por: Cerezales, Mónica, et al.
Publicado: (2020)

Contribution of RND-Type Efflux Pumps in Reduced Susceptibility to Biocides in Acinetobacter baumannii
por: Meyer, Christina, et al.
Publicado: (2022)

adeABC efflux gene in Acinetobacter baumannii
por: Xu, C., et al.
Publicado: (2019)

High Frequency of AdeA, AdeB and AdeC Genes among Acinetobacter baumannii Isolates
por: RANJBAR, Reza, et al.
Publicado: (2020)

In vitro synergistic effect of amlodipine and imipenem on the expression of the AdeABC efflux pump in multidrug-resistant Acinetobacter baumannii
por: Hu, Chao, et al.
Publicado: (2018)

Cryo-EM Determination of Eravacycline-Bound Structures of the Ribosome and the Multidrug Efflux Pump AdeJ of Acinetobacter baumannii
por: Zhang, Zhemin, et al.
Publicado: (2021)

Novel tigecycline resistance mechanisms in Acinetobacter baumannii mediated by mutations in adeS, rpoB and rrf
por: Hua, Xiaoting, et al.
Publicado: (2021)

Alteration of adeS Contributes to Tigecycline Resistance and Collateral Sensitivity to Sulbactam in Acinetobacter baumannii
por: Yang, Yunxing, et al.
Publicado: (2023)

Molecular Epidemiology of Carbapenem-Resistant Acinetobacter baumannii From Khartoum State, Sudan
por: Al-Hassan, Leena, et al.
Publicado: (2021)

First Report of New Delhi Metallo-β-Lactamase-6 (NDM-6) in a Clinical Acinetobacter baumannii Isolate From Northern Spain
por: Xanthopoulou, Kyriaki, et al.
Publicado: (2020)

An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii
por: Morgan, Christopher E., et al.
Publicado: (2022)

Correlation of Ciprofloxacin Resistance with the AdeABC Efflux System in Acinetobacter baumannii Clinical Isolates
por: Ardebili, Abdollah, et al.
Publicado: (2014)

Role of Aders and OXA23 Genes among Imipenem Resistant Acinetobacter baumannii Isolates from Two Hospitals of Tehran, Iran
por: Ostad Asadolah-Malayeri, Helia, et al.
Publicado: (2016)

Role of the BaeSR two-component system in the regulation of Acinetobacter baumannii adeAB genes and its correlation with tigecycline susceptibility
por: Lin, Ming-Feng, et al.
Publicado: (2014)

Rescued chlorhexidine activity by resveratrol against carbapenem-resistant Acinetobacter baumannii via down-regulation of AdeB efflux pump
por: Singkham-in, Uthaibhorn, et al.
Publicado: (2020)

Riparin-B as a Potential Inhibitor of AdeABC Efflux System from Acinetobacter baumannii
por: Leão, Patrícia Virna Sales, et al.
Publicado: (2023)

The Inhibitory Effect of Thioridazine on adeB Efflux Pump Gene Expression in Multidrug-Resistant Acinetobacter baumannii Isolates Using Real Time PCR
por: Ahmadi, Fereshteh, et al.
Publicado: (2022)

Multidrug-Resistant Acinetobacter baumannii
por: Abbo, Aharon, et al.
Publicado: (2005)

Multidrug-Resistant Acinetobacter baumannii
por: Krcmery, Vladimir, et al.
Publicado: (2007)

Correction: Rescued chlorhexidine activity by resveratrol against carbapenem-resistant Acinetobacter baumannii via down-regulation of AdeB efflux pump
por: Singkham-in, Uthaibhorn, et al.
Publicado: (2022)

Contribution of the Ade Resistance-Nodulation-Cell Division-Type Efflux Pumps to Fitness and Pathogenesis of Acinetobacter baumannii
por: Yoon, Eun-Jeong, et al.
Publicado: (2016)

Multidrug-resistant Acinetobacter baumannii, Russia
por: Naas, Thierry, et al.
Publicado: (2007)

Multidrug-Resistant Acinetobacter baumannii in Jordan
por: Al-Tamimi, Mohammad, et al.
Publicado: (2022)

Antibiotic resistance assessment of Acinetobacter baumannii isolates from Tehran hospitals due to the presence of efflux pumps encoding genes (adeA and adeS genes) by molecular method
por: Basatian-Tashkan, Batool, et al.
Publicado: (2020)

A Truncated AdeS Kinase Protein Generated by ISAba1 Insertion Correlates with Tigecycline Resistance in Acinetobacter baumannii
por: Sun, Jun-Ren, et al.
Publicado: (2012)

Genomic Analysis of Carbapenem-Resistant Acinetobacter baumannii Isolates Belonging to Major Endemic Clones in South America
por: Nodari, Carolina Silva, et al.
Publicado: (2020)

Prevalence of Genes of OXA-23 Carbapenemase and AdeABC Efflux Pump Associated with Multidrug Resistance of Acinetobacter baumannii Isolates in the ICU of a Comprehensive Hospital of Northwestern China
por: Jia, Wei, et al.
Publicado: (2015)

First person – Flavie Ader
Publicado: (2022)

Comparative Genomics of Multidrug Resistance in Acinetobacter baumannii
por: Fournier, Pierre-Edouard, et al.
Publicado: (2006)

Optimal Therapy for Multidrug-Resistant Acinetobacter baumannii
por: Cunha, Burke A.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_0eg2ra01087d90mr7b8bk5c0cp