BAY61-3606 attenuates neuroinflammation and neurofunctional damage by inhibiting microglial Mincle/Syk signaling response after traumatic brain injury

Neuroinflammatory processes mediated by microglial activation and subsequent neuronal damage are the hallmarks of traumatic brain injury (TBI). As an inhibitor of the macrophage-inducible C-type lectin (Mincle)/spleen tyrosine kinase (Syk) signaling pathway, BAY61-3606 (BAY) has previously demonstra...

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Detalles Bibliográficos
Autores principales: He, Xuejun, Huang, Yimin, Liu, Yanchao, Zhang, Xincheng, Yue, Pengjie, Ma, Xiaopeng, Miao, Zhuangzhuang, Long, Xiaobing, Yang, Yiping, Wan, Xueyan, Lei, Jin, Shu, Kai, Lei, Ting, Gan, Chao, Zhang, Huaqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612304/
https://www.ncbi.nlm.nih.gov/pubmed/34751408
http://dx.doi.org/10.3892/ijmm.2021.5060

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