Single-Domain Antibody Nuclear Imaging Allows Noninvasive Quantification of LAG-3 Expression by Tumor-Infiltrating Leukocytes and Predicts Response of Immune Checkpoint Blockade

Recent advances in the field of immune-oncology led to the discovery of next-generation immune checkpoints (ICPs). Lymphocyte activation gene-3 (LAG-3), being the most widely studied among them, is being explored as a target for the treatment of cancer patients. Several antagonistic anti-LAG-3 antib...

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Detalles Bibliográficos
Autores principales: Lecocq, Quentin, Awad, Robin Maximilian, De Vlaeminck, Yannick, de Mey, Wout, Ertveldt, Thomas, Goyvaerts, Cleo, Raes, Geert, Thielemans, Kris, Keyaerts, Marleen, Devoogdt, Nick, Breckpot, Karine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2021
Materias:
Featured Basic Science Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612328/
https://www.ncbi.nlm.nih.gov/pubmed/33712537
http://dx.doi.org/10.2967/jnumed.120.258871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612328/
https://www.ncbi.nlm.nih.gov/pubmed/33712537
http://dx.doi.org/10.2967/jnumed.120.258871

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