First report on molecular docking analysis and drug resistance substitutions to approved HCV NS5A and NS5B inhibitors amongst Iranian patients

BACKGROUND: NS5A and NS5B proteins of hepatitis C virus (HCV) are the main targets of compounds that directly inhibit HCV infections. However, the emergence of resistance-associated substitutions (RASs) may cause substantial reductions in susceptibility to inhibitors. METHODS: Viral load and genotyp...

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Detalles Bibliográficos
Autores principales: Hasanshahi, Zahra, Hashempour, Ava, Ghasabi, Farzane, Moayedi, Javad, Musavi, Zahra, Dehghani, Behzad, Sharafi, Heidar, Joulaei, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612383/
https://www.ncbi.nlm.nih.gov/pubmed/34819046
http://dx.doi.org/10.1186/s12876-021-01988-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612383/
https://www.ncbi.nlm.nih.gov/pubmed/34819046
http://dx.doi.org/10.1186/s12876-021-01988-y

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