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Correlative 3D cryo X-ray imaging reveals intracellular location and effect of designed antifibrotic protein–nanomaterial hybrids

Revealing the intracellular location of novel therapeutic agents is paramount for the understanding of their effect at the cell ultrastructure level. Here, we apply a novel correlative cryo 3D imaging approach to determine the intracellular fate of a designed protein–nanomaterial hybrid with antifib...

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Detalles Bibliográficos
Autores principales: Groen, J., Palanca, A., Aires, A., Conesa, J. J., Maestro, D., Rehbein, S., Harkiolaki, M., Villar, A. V., Cortajarena, A. L., Pereiro, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612387/
https://www.ncbi.nlm.nih.gov/pubmed/34909150
http://dx.doi.org/10.1039/d1sc04183e