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A shared transcriptional code orchestrates temporal patterning of the central nervous system

The molecular mechanisms that produce the full array of neuronal subtypes in the vertebrate nervous system are incompletely understood. Here, we provide evidence of a global temporal patterning program comprising sets of transcription factors that stratifies neurons based on the developmental time a...

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Detalles Bibliográficos
Autores principales: Sagner, Andreas, Zhang, Isabel, Watson, Thomas, Lazaro, Jorge, Melchionda, Manuela, Briscoe, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612522/
https://www.ncbi.nlm.nih.gov/pubmed/34767545
http://dx.doi.org/10.1371/journal.pbio.3001450