Targeted chromosomal Escherichia coli:dnaB exterior surface residues regulate DNA helicase behavior to maintain genomic stability and organismal fitness

Helicase regulation involves modulation of unwinding speed to maintain coordination of DNA replication fork activities and is vital for replisome progression. Currently, mechanisms for helicase regulation that involve interactions with both DNA strands through a steric exclusion and wrapping (SEW) m...

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Detalles Bibliográficos
Autores principales: Behrmann, Megan S., Perera, Himasha M., Hoang, Joy M., Venkat, Trisha A., Visser, Bryan J., Bates, David, Trakselis, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612530/
https://www.ncbi.nlm.nih.gov/pubmed/34767550
http://dx.doi.org/10.1371/journal.pgen.1009886

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