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DNA double strand break position leads to distinct gene expression changes and regulates VSG switching pathway choice

Antigenic variation is an immune evasion strategy used by Trypanosoma brucei that results in the periodic exchange of the surface protein coat. This process is facilitated by the movement of variant surface glycoprotein genes in or out of a specialized locus known as bloodstream form expression site...

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Detalles Bibliográficos
Autores principales: Thivolle, Alix, Mehnert, Ann-Kathrin, Tihon, Eliane, McLaughlin, Emilia, Dujeancourt-Henry, Annick, Glover, Lucy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612549/
https://www.ncbi.nlm.nih.gov/pubmed/34767618
http://dx.doi.org/10.1371/journal.ppat.1010038