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Live imaging reveals the cellular events downstream of SARM1 activation
SARM1 is an inducible NAD(+) hydrolase that triggers axon loss and neuronal cell death in the injured and diseased nervous system. While SARM1 activation and enzyme function are well defined, the cellular events downstream of SARM1 activity but prior to axonal demise are much less well understood. D...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612704/ https://www.ncbi.nlm.nih.gov/pubmed/34779400 http://dx.doi.org/10.7554/eLife.71148 |