Effects of antibiotic resistance, drug target attainment, bacterial pathogenicity and virulence, and antibiotic access and affordability on outcomes in neonatal sepsis: an international microbiology and drug evaluation prospective substudy (BARNARDS)

BACKGROUND: Sepsis is a major contributor to neonatal mortality, particularly in low-income and middle-income countries (LMICs). WHO advocates ampicillin–gentamicin as first-line therapy for the management of neonatal sepsis. In the BARNARDS observational cohort study of neonatal sepsis and antimicr...

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Autores principales: Thomson, Kathryn M, Dyer, Calie, Liu, Feiyan, Sands, Kirsty, Portal, Edward, Carvalho, Maria J, Barrell, Matthew, Boostrom, Ian, Dunachie, Susanna, Farzana, Refath, Ferreira, Ana, Frayne, Francis, Hassan, Brekhna, Jones, Ellis, Jones, Lim, Mathias, Jordan, Milton, Rebecca, Rees, Jessica, Chan, Grace J, Bekele, Delayehu, Mahlet, Abayneh, Basu, Sulagna, Nandy, Ranjan K, Saha, Bijan, Iregbu, Kenneth, Modibbo, Fatima, Uwaezuoke, Stella, Zahra, Rabaab, Shirazi, Haider, Syed, Najeeb U, Mazarati, Jean-Baptiste, Rucogoza, Aniceth, Gaju, Lucie, Mehtar, Shaheen, Bulabula, Andre N H, Whitelaw, Andrew, van Hasselt, Johan G C, Walsh, Timothy R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science ;, The Lancet Pub. Group 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612937/
https://www.ncbi.nlm.nih.gov/pubmed/34384533
http://dx.doi.org/10.1016/S1473-3099(21)00050-5

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