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Anti-pathogen stainless steel combating COVID-19

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibits strong stability on conventional stainless steel (SS) surface, with infectious virus detected even after two days, posing a high risk of virus transmission via surface touching in public areas. In order to mitigate the surface tou...

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Autores principales: Liu, L.T., Chin, A.W.H., Yu, P., Poon, L.L.M., Huang, M.X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613009/
https://www.ncbi.nlm.nih.gov/pubmed/34853550
http://dx.doi.org/10.1016/j.cej.2021.133783
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author Liu, L.T.
Chin, A.W.H.
Yu, P.
Poon, L.L.M.
Huang, M.X.
author_facet Liu, L.T.
Chin, A.W.H.
Yu, P.
Poon, L.L.M.
Huang, M.X.
author_sort Liu, L.T.
collection PubMed
description Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibits strong stability on conventional stainless steel (SS) surface, with infectious virus detected even after two days, posing a high risk of virus transmission via surface touching in public areas. In order to mitigate the surface toughing transmission, the present study develops the first SS with excellent anti-pathogen properties against SARS-COV-2. The stabilities of SARS-CoV-2, H1N1 influenza A virus (H1N1), and Escherichia coli (E.coli) on the surfaces of Cu-contained SS, pure Cu, Ag-contained SS, and pure Ag were investigated. It is discovered that pure Ag and Ag-contained SS surfaces do not display apparent inhibitory effects on SARS-CoV-2 and H1N1. In comparison, both pure Cu and Cu-contained SS with a high Cu content exhibit significant antiviral properties. Significantly, the developed anti-pathogen SS with 20 wt% Cu can distinctly reduce 99.75% and 99.99% of viable SARS-CoV-2 on its surface within 3 and 6 h, respectively. In addition, the present anti-pathogen SS also exhibits an excellent inactivation ability for H1N1 influenza A virus (H1N1), and Escherichia coli (E.coli). Interestingly, the Cu ion concentration released from the anti-pathogen SS with 10 wt% and 20 wt% Cu was notably higher than the Ag ion concentration released from Ag and the Ag-contained SS. Lift buttons made of the present anti-pathogen SS are produced using mature powder metallurgy technique, demonstrating its potential applications in public areas and fighting the transmission of SARS-CoV-2 and other pathogens via surface touching.
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spelling pubmed-86130092021-11-26 Anti-pathogen stainless steel combating COVID-19 Liu, L.T. Chin, A.W.H. Yu, P. Poon, L.L.M. Huang, M.X. Chem Eng J Article Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibits strong stability on conventional stainless steel (SS) surface, with infectious virus detected even after two days, posing a high risk of virus transmission via surface touching in public areas. In order to mitigate the surface toughing transmission, the present study develops the first SS with excellent anti-pathogen properties against SARS-COV-2. The stabilities of SARS-CoV-2, H1N1 influenza A virus (H1N1), and Escherichia coli (E.coli) on the surfaces of Cu-contained SS, pure Cu, Ag-contained SS, and pure Ag were investigated. It is discovered that pure Ag and Ag-contained SS surfaces do not display apparent inhibitory effects on SARS-CoV-2 and H1N1. In comparison, both pure Cu and Cu-contained SS with a high Cu content exhibit significant antiviral properties. Significantly, the developed anti-pathogen SS with 20 wt% Cu can distinctly reduce 99.75% and 99.99% of viable SARS-CoV-2 on its surface within 3 and 6 h, respectively. In addition, the present anti-pathogen SS also exhibits an excellent inactivation ability for H1N1 influenza A virus (H1N1), and Escherichia coli (E.coli). Interestingly, the Cu ion concentration released from the anti-pathogen SS with 10 wt% and 20 wt% Cu was notably higher than the Ag ion concentration released from Ag and the Ag-contained SS. Lift buttons made of the present anti-pathogen SS are produced using mature powder metallurgy technique, demonstrating its potential applications in public areas and fighting the transmission of SARS-CoV-2 and other pathogens via surface touching. Elsevier B.V. 2022-04-01 2021-11-25 /pmc/articles/PMC8613009/ /pubmed/34853550 http://dx.doi.org/10.1016/j.cej.2021.133783 Text en © 2021 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Liu, L.T.
Chin, A.W.H.
Yu, P.
Poon, L.L.M.
Huang, M.X.
Anti-pathogen stainless steel combating COVID-19
title Anti-pathogen stainless steel combating COVID-19
title_full Anti-pathogen stainless steel combating COVID-19
title_fullStr Anti-pathogen stainless steel combating COVID-19
title_full_unstemmed Anti-pathogen stainless steel combating COVID-19
title_short Anti-pathogen stainless steel combating COVID-19
title_sort anti-pathogen stainless steel combating covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613009/
https://www.ncbi.nlm.nih.gov/pubmed/34853550
http://dx.doi.org/10.1016/j.cej.2021.133783
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