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Review of Transporter Substrate, Inhibitor, and Inducer Characteristics of Cladribine

Cladribine is a nucleoside analog that is phosphorylated in its target cells (B- and T-lymphocytes) to its active adenosine triphosphate form (2-chlorodeoxyadenosine triphosphate). Cladribine tablets 10 mg (Mavenclad(®)) administered for up to 10 days per year in 2 consecutive years (3.5-mg/kg cumul...

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Detalles Bibliográficos
Autores principales: Hermann, Robert, Krajcsi, Peter, Fluck, Markus, Seithel-Keuth, Annick, Bytyqi, Afrim, Galazka, Andrew, Munafo, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613159/
https://www.ncbi.nlm.nih.gov/pubmed/34435310
http://dx.doi.org/10.1007/s40262-021-01065-3