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Review of Transporter Substrate, Inhibitor, and Inducer Characteristics of Cladribine
Cladribine is a nucleoside analog that is phosphorylated in its target cells (B- and T-lymphocytes) to its active adenosine triphosphate form (2-chlorodeoxyadenosine triphosphate). Cladribine tablets 10 mg (Mavenclad(®)) administered for up to 10 days per year in 2 consecutive years (3.5-mg/kg cumul...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613159/ https://www.ncbi.nlm.nih.gov/pubmed/34435310 http://dx.doi.org/10.1007/s40262-021-01065-3 |