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An evolutionary functional genomics approach identifies novel candidate regions involved in isoniazid resistance in Mycobacterium tuberculosis

Efforts to eradicate tuberculosis are hampered by the rise and spread of antibiotic resistance. Several large-scale projects have aimed to specifically link clinical mutations to resistance phenotypes, but they were limited in both their explanatory and predictive powers. Here, we combine functional...

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Detalles Bibliográficos
Autores principales:	Furió, Victoria, Moreno-Molina, Miguel, Chiner-Oms, Álvaro, Villamayor, Luis M., Torres-Puente, Manuela, Comas, Iñaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613195/ https://www.ncbi.nlm.nih.gov/pubmed/34819627 http://dx.doi.org/10.1038/s42003-021-02846-z

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