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Trigeminal neuropathy: Two case reports of gasserian ganglion stimulation

This report describes the successful treatment of two patients with trigeminal neuropathy by using gasserian ganglion stimulation. Case reports: The first case report deals with a 53‐year‐old woman suffering from right‐sided facial pain after a gamma knife lesion for schwannoma of the right inner ea...

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Autores principales: Logghe, Yannick, Smet, Iris, Jerjir, Ali, Verelst, Peter, Devos, Marieke, Van Buyten, Jean‐Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613404/
https://www.ncbi.nlm.nih.gov/pubmed/34661988
http://dx.doi.org/10.1002/brb3.2379
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author Logghe, Yannick
Smet, Iris
Jerjir, Ali
Verelst, Peter
Devos, Marieke
Van Buyten, Jean‐Pierre
author_facet Logghe, Yannick
Smet, Iris
Jerjir, Ali
Verelst, Peter
Devos, Marieke
Van Buyten, Jean‐Pierre
author_sort Logghe, Yannick
collection PubMed
description This report describes the successful treatment of two patients with trigeminal neuropathy by using gasserian ganglion stimulation. Case reports: The first case report deals with a 53‐year‐old woman suffering from right‐sided facial pain after a gamma knife lesion for schwannoma of the right inner ear. For 9 years, several interventions with the aim of relieving the pain were unsuccessful; in fact, they had aggravated the symptoms. A trial with a neurostimulator at the level of the Gasser ganglion had an immediately positive effect on her score for facial pain, which decreased from 7.3 to 0 on a visual analog scale, assessed during a period of 2 months. Additionally, the patient had weaned off all her medication by the end of the period. The second case report describes a 64‐year‐old man suffering from trigeminal neuropathy, which mainly manifested itself as an itch. For a period of 15 years, neither medication nor several interventions were effective. A trial with an electrode at the level of the Gasser ganglion reduced his pain score from 7.0 to 1.5 on a visual analog scale, assessed during a period of three months. His medication could be limited to pregabalin 150 mg bidaily. In contrast, prior to the implantation, his oral medication consisted of pregabalin 75 mg up to five times a day. Conclusion: These case reports show that stimulation of the gasserian ganglion is a successful, minimally invasive, and non‐destructive treatment in refractory trigeminal neuropathy and should be considered earlier in the treatment algorithm of trigeminal neuropathy.
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spelling pubmed-86134042021-11-30 Trigeminal neuropathy: Two case reports of gasserian ganglion stimulation Logghe, Yannick Smet, Iris Jerjir, Ali Verelst, Peter Devos, Marieke Van Buyten, Jean‐Pierre Brain Behav Original Articles This report describes the successful treatment of two patients with trigeminal neuropathy by using gasserian ganglion stimulation. Case reports: The first case report deals with a 53‐year‐old woman suffering from right‐sided facial pain after a gamma knife lesion for schwannoma of the right inner ear. For 9 years, several interventions with the aim of relieving the pain were unsuccessful; in fact, they had aggravated the symptoms. A trial with a neurostimulator at the level of the Gasser ganglion had an immediately positive effect on her score for facial pain, which decreased from 7.3 to 0 on a visual analog scale, assessed during a period of 2 months. Additionally, the patient had weaned off all her medication by the end of the period. The second case report describes a 64‐year‐old man suffering from trigeminal neuropathy, which mainly manifested itself as an itch. For a period of 15 years, neither medication nor several interventions were effective. A trial with an electrode at the level of the Gasser ganglion reduced his pain score from 7.0 to 1.5 on a visual analog scale, assessed during a period of three months. His medication could be limited to pregabalin 150 mg bidaily. In contrast, prior to the implantation, his oral medication consisted of pregabalin 75 mg up to five times a day. Conclusion: These case reports show that stimulation of the gasserian ganglion is a successful, minimally invasive, and non‐destructive treatment in refractory trigeminal neuropathy and should be considered earlier in the treatment algorithm of trigeminal neuropathy. John Wiley and Sons Inc. 2021-10-17 /pmc/articles/PMC8613404/ /pubmed/34661988 http://dx.doi.org/10.1002/brb3.2379 Text en © 2021 The Authors. Brain and Behavior published by Wiley Periodicals LLC https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Logghe, Yannick
Smet, Iris
Jerjir, Ali
Verelst, Peter
Devos, Marieke
Van Buyten, Jean‐Pierre
Trigeminal neuropathy: Two case reports of gasserian ganglion stimulation
title Trigeminal neuropathy: Two case reports of gasserian ganglion stimulation
title_full Trigeminal neuropathy: Two case reports of gasserian ganglion stimulation
title_fullStr Trigeminal neuropathy: Two case reports of gasserian ganglion stimulation
title_full_unstemmed Trigeminal neuropathy: Two case reports of gasserian ganglion stimulation
title_short Trigeminal neuropathy: Two case reports of gasserian ganglion stimulation
title_sort trigeminal neuropathy: two case reports of gasserian ganglion stimulation
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613404/
https://www.ncbi.nlm.nih.gov/pubmed/34661988
http://dx.doi.org/10.1002/brb3.2379
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