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Combining Network Pharmacology with Molecular Docking for Mechanistic Research on Thyroid Dysfunction Caused by Polybrominated Diphenyl Ethers and Their Metabolites
Network pharmacology was used to illuminate the targets and pathways of polybrominated diphenyl ethers (PBDEs) causing thyroid dysfunction. A protein-protein interaction (PPI) network was constructed. Molecular docking was applied to analyze PBDEs and key targets according to the network pharmacolog...
Autores principales: | He, Qiaoyu, Chen, Xiaopeng, Liu, Jing, Li, Chunxia, Xing, Hong, Shi, Yumeng, Tang, Qian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613503/ https://www.ncbi.nlm.nih.gov/pubmed/34840968 http://dx.doi.org/10.1155/2021/2961747 |
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