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Real‐time deep artifact suppression using recurrent U‐Nets for low‐latency cardiac MRI

PURPOSE: Real‐time low latency MRI is performed to guide various cardiac interventions. Real‐time acquisitions often require iterative image reconstruction strategies, which lead to long reconstruction times. In this study, we aim to reconstruct highly undersampled radial real‐time data with low lat...

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Autores principales: Jaubert, Olivier, Montalt‐Tordera, Javier, Knight, Dan, Coghlan, Gerry J., Arridge, Simon, Steeden, Jennifer A., Muthurangu, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613539/
https://www.ncbi.nlm.nih.gov/pubmed/34032308
http://dx.doi.org/10.1002/mrm.28834
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author Jaubert, Olivier
Montalt‐Tordera, Javier
Knight, Dan
Coghlan, Gerry J.
Arridge, Simon
Steeden, Jennifer A.
Muthurangu, Vivek
author_facet Jaubert, Olivier
Montalt‐Tordera, Javier
Knight, Dan
Coghlan, Gerry J.
Arridge, Simon
Steeden, Jennifer A.
Muthurangu, Vivek
author_sort Jaubert, Olivier
collection PubMed
description PURPOSE: Real‐time low latency MRI is performed to guide various cardiac interventions. Real‐time acquisitions often require iterative image reconstruction strategies, which lead to long reconstruction times. In this study, we aim to reconstruct highly undersampled radial real‐time data with low latency using deep learning. METHODS: A 2D U‐Net with convolutional long short‐term memory layers is proposed to exploit spatial and preceding temporal information to reconstruct highly accelerated tiny golden radial data with low latency. The network was trained using a dataset of breath‐hold CINE data (including 770 time series from 7 different orientations). Synthetic paired data were created by retrospectively undersampling the magnitude images, and the network was trained to recover the target images. In the spirit of interventional imaging, the network was trained and tested for varying acceleration rates and orientations. Data were prospectively acquired and reconstructed in real time in 1 healthy subject interactively and in 3 patients who underwent catheterization. Images were visually compared to sliding window and compressed sensing reconstructions and a conventional Cartesian real‐time sequence. RESULTS: The proposed network generalized well to different acceleration rates and unseen orientations for all considered metrics in simulated data (less than 4% reduction in structural similarity index compared to similar acceleration and orientation‐specific networks). The proposed reconstruction was demonstrated interactively, successfully depicting catheters in vivo with low latency (39 ms, including 19 ms for deep artifact suppression) and an image quality comparing favorably to other reconstructions. CONCLUSION: Deep artifact suppression was successfully demonstrated in the time‐critical application of non‐Cartesian real‐time interventional cardiac MR.
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spelling pubmed-86135392021-11-29 Real‐time deep artifact suppression using recurrent U‐Nets for low‐latency cardiac MRI Jaubert, Olivier Montalt‐Tordera, Javier Knight, Dan Coghlan, Gerry J. Arridge, Simon Steeden, Jennifer A. Muthurangu, Vivek Magn Reson Med Research Articles—Imaging Methodology PURPOSE: Real‐time low latency MRI is performed to guide various cardiac interventions. Real‐time acquisitions often require iterative image reconstruction strategies, which lead to long reconstruction times. In this study, we aim to reconstruct highly undersampled radial real‐time data with low latency using deep learning. METHODS: A 2D U‐Net with convolutional long short‐term memory layers is proposed to exploit spatial and preceding temporal information to reconstruct highly accelerated tiny golden radial data with low latency. The network was trained using a dataset of breath‐hold CINE data (including 770 time series from 7 different orientations). Synthetic paired data were created by retrospectively undersampling the magnitude images, and the network was trained to recover the target images. In the spirit of interventional imaging, the network was trained and tested for varying acceleration rates and orientations. Data were prospectively acquired and reconstructed in real time in 1 healthy subject interactively and in 3 patients who underwent catheterization. Images were visually compared to sliding window and compressed sensing reconstructions and a conventional Cartesian real‐time sequence. RESULTS: The proposed network generalized well to different acceleration rates and unseen orientations for all considered metrics in simulated data (less than 4% reduction in structural similarity index compared to similar acceleration and orientation‐specific networks). The proposed reconstruction was demonstrated interactively, successfully depicting catheters in vivo with low latency (39 ms, including 19 ms for deep artifact suppression) and an image quality comparing favorably to other reconstructions. CONCLUSION: Deep artifact suppression was successfully demonstrated in the time‐critical application of non‐Cartesian real‐time interventional cardiac MR. John Wiley and Sons Inc. 2021-05-25 2021-10 /pmc/articles/PMC8613539/ /pubmed/34032308 http://dx.doi.org/10.1002/mrm.28834 Text en © 2021 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles—Imaging Methodology
Jaubert, Olivier
Montalt‐Tordera, Javier
Knight, Dan
Coghlan, Gerry J.
Arridge, Simon
Steeden, Jennifer A.
Muthurangu, Vivek
Real‐time deep artifact suppression using recurrent U‐Nets for low‐latency cardiac MRI
title Real‐time deep artifact suppression using recurrent U‐Nets for low‐latency cardiac MRI
title_full Real‐time deep artifact suppression using recurrent U‐Nets for low‐latency cardiac MRI
title_fullStr Real‐time deep artifact suppression using recurrent U‐Nets for low‐latency cardiac MRI
title_full_unstemmed Real‐time deep artifact suppression using recurrent U‐Nets for low‐latency cardiac MRI
title_short Real‐time deep artifact suppression using recurrent U‐Nets for low‐latency cardiac MRI
title_sort real‐time deep artifact suppression using recurrent u‐nets for low‐latency cardiac mri
topic Research Articles—Imaging Methodology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613539/
https://www.ncbi.nlm.nih.gov/pubmed/34032308
http://dx.doi.org/10.1002/mrm.28834
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