Cargando…
CPEB1, a novel risk gene in recent-onset schizophrenia, contributes to mitochondrial complex I defect caused by a defective provirus ERVWE1
BACKGROUND: Schizophrenia afflicts 1% of the world population. Clinical studies suggest that schizophrenia patients may have an imbalance of mitochondrial energy metabolism via inhibition of mitochondrial complex I activity. Moreover, recent studies have shown that ERVWE1 is also a risk factor for s...
Autores principales: | Xia, Ya-Ru, Wei, Xiao-Cui, Li, Wen-Shi, Yan, Qiu-Jin, Wu, Xiu-Lin, Yao, Wei, Li, Xu-Hang, Zhu, Fan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613759/ https://www.ncbi.nlm.nih.gov/pubmed/34888175 http://dx.doi.org/10.5498/wjp.v11.i11.1075 |
Ejemplares similares
-
ERVW-1 Activates ATF6-Mediated Unfolded Protein Response by Decreasing GANAB in Recent-Onset Schizophrenia
por: Xue, Xing, et al.
Publicado: (2023) -
Long-term persistence of transcriptionally active ‘defective’ HIV-1 proviruses: implications for persistent immune activation during antiretroviral therapy
por: Singh, Kanal, et al.
Publicado: (2023) -
Defective HIV-1 proviruses produce viral proteins
por: Imamichi, Hiromi, et al.
Publicado: (2020) -
Defective proviruses rapidly accumulate during acute HIV-1 infection
por: Bruner, Katherine M., et al.
Publicado: (2016) -
Intragenic proviral elements support transcription of defective HIV-1 proviruses
por: Kuniholm, Jeffrey, et al.
Publicado: (2021)