Accurate haplotype-resolved assembly reveals the origin of structural variants for human trios

MOTIVATION: Achieving a near complete understanding of how the genome of an individual affects the phenotypes of that individual requires deciphering the order of variations along homologous chromosomes in species with diploid genomes. However, true diploid assembly of long-range haplotypes remains...

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Detalles Bibliográficos
Autores principales: Xu, Mengyang, Guo, Lidong, Du, Xiao, Li, Lei, Peters, Brock A, Deng, Li, Wang, Ou, Chen, Fang, Wang, Jun, Jiang, Zhesheng, Han, Jinglin, Ni, Ming, Yang, Huanming, Xu, Xun, Liu, Xin, Huang, Jie, Fan, Guangyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613828/
https://www.ncbi.nlm.nih.gov/pubmed/33538292
http://dx.doi.org/10.1093/bioinformatics/btab068

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