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Leveraging ageing models of pulmonary fibrosis: the efficacy of nintedanib in ageing

Although nintedanib is overwhelmingly prescribed to elderly patients, this is the first study to demonstrate that ageing does not impact the efficacy of nintedanib. This study sheds light on the utility of aged animal models in pulmonary fibrosis. https://bit.ly/3zA9RC5

Detalles Bibliográficos
Autores principales: Kato, Kosuke, Shin, Yoon-Joo, Palumbo, Sunny, Papageorgiou, Ioannis, Hahn, Seongmin, Irish, Joseph D., Rounseville, Skye P., Krafty, Robert T., Wollin, Lutz, Sauler, Maor, Hecker, Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613836/
https://www.ncbi.nlm.nih.gov/pubmed/34531276
http://dx.doi.org/10.1183/13993003.00759-2021
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author Kato, Kosuke
Shin, Yoon-Joo
Palumbo, Sunny
Papageorgiou, Ioannis
Hahn, Seongmin
Irish, Joseph D.
Rounseville, Skye P.
Krafty, Robert T.
Wollin, Lutz
Sauler, Maor
Hecker, Louise
author_facet Kato, Kosuke
Shin, Yoon-Joo
Palumbo, Sunny
Papageorgiou, Ioannis
Hahn, Seongmin
Irish, Joseph D.
Rounseville, Skye P.
Krafty, Robert T.
Wollin, Lutz
Sauler, Maor
Hecker, Louise
author_sort Kato, Kosuke
collection PubMed
description Although nintedanib is overwhelmingly prescribed to elderly patients, this is the first study to demonstrate that ageing does not impact the efficacy of nintedanib. This study sheds light on the utility of aged animal models in pulmonary fibrosis. https://bit.ly/3zA9RC5
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spelling pubmed-86138362021-11-26 Leveraging ageing models of pulmonary fibrosis: the efficacy of nintedanib in ageing Kato, Kosuke Shin, Yoon-Joo Palumbo, Sunny Papageorgiou, Ioannis Hahn, Seongmin Irish, Joseph D. Rounseville, Skye P. Krafty, Robert T. Wollin, Lutz Sauler, Maor Hecker, Louise Eur Respir J Agora Although nintedanib is overwhelmingly prescribed to elderly patients, this is the first study to demonstrate that ageing does not impact the efficacy of nintedanib. This study sheds light on the utility of aged animal models in pulmonary fibrosis. https://bit.ly/3zA9RC5 European Respiratory Society 2021-11-25 /pmc/articles/PMC8613836/ /pubmed/34531276 http://dx.doi.org/10.1183/13993003.00759-2021 Text en Copyright ©The authors 2021. https://creativecommons.org/licenses/by-nc/4.0/This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ersnet.org (mailto:permissions@ersnet.org)
spellingShingle Agora
Kato, Kosuke
Shin, Yoon-Joo
Palumbo, Sunny
Papageorgiou, Ioannis
Hahn, Seongmin
Irish, Joseph D.
Rounseville, Skye P.
Krafty, Robert T.
Wollin, Lutz
Sauler, Maor
Hecker, Louise
Leveraging ageing models of pulmonary fibrosis: the efficacy of nintedanib in ageing
title Leveraging ageing models of pulmonary fibrosis: the efficacy of nintedanib in ageing
title_full Leveraging ageing models of pulmonary fibrosis: the efficacy of nintedanib in ageing
title_fullStr Leveraging ageing models of pulmonary fibrosis: the efficacy of nintedanib in ageing
title_full_unstemmed Leveraging ageing models of pulmonary fibrosis: the efficacy of nintedanib in ageing
title_short Leveraging ageing models of pulmonary fibrosis: the efficacy of nintedanib in ageing
title_sort leveraging ageing models of pulmonary fibrosis: the efficacy of nintedanib in ageing
topic Agora
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613836/
https://www.ncbi.nlm.nih.gov/pubmed/34531276
http://dx.doi.org/10.1183/13993003.00759-2021
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