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Protein Engineering in the Design of Protein–Protein Interactions: SARS-CoV-2 Inhibitors as a Test Case
[Image: see text] The formation of specific protein–protein interactions (PPIs) drive most biological processes. Malfunction of such interactions is the molecular driver of many diseases. Our ability to engineer existing PPIs or create new ones has become a vital research tool. In addition, engineer...
Autores principales: | Zahradník, Jiří, Schreiber, Gideon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613841/ https://www.ncbi.nlm.nih.gov/pubmed/34196543 http://dx.doi.org/10.1021/acs.biochem.1c00356 |
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