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Epigenetic activation of the elongator complex sensitizes gallbladder cancer to gemcitabine therapy

BACKGROUND: Gallbladder cancer (GBC) is known for its high malignancy and multidrug resistance. Previously, we uncovered that impaired integrity and stability of the elongator complex leads to GBC chemotherapy resistance, but whether its restoration can be an efficient therapeutic strategy for GBC r...

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Detalles Bibliográficos
Autores principales:	Xu, Sunwang, Jiang, Cen, Lin, Ruirong, Wang, Xiaopeng, Hu, Xiaoqiang, Chen, Wei, Chen, Xiangjin, Chen, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613969/ https://www.ncbi.nlm.nih.gov/pubmed/34823564 http://dx.doi.org/10.1186/s13046-021-02186-0

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