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Elp1 facilitates RAD51-mediated homologous recombination repair via translational regulation
BACKGROUND: RAD51-dependent homologous recombination (HR) is one of the most important pathways for repairing DNA double-strand breaks (DSBs), and its regulation is crucial to maintain genome integrity. Elp1 gene encodes IKAP/ELP1, a core subunit of the Elongator complex, which has been implicated i...
Autores principales: | Chen, Wei-Ting, Tseng, Huan-Yi, Jiang, Chung-Lin, Lee, Chih-Ying, Chi, Peter, Chen, Liuh-Yow, Lo, Kai-Yin, Wang, I-Ching, Lin, Fu-Jung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613991/ https://www.ncbi.nlm.nih.gov/pubmed/34819065 http://dx.doi.org/10.1186/s12929-021-00773-z |
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