Antitumor effects of the small molecule DMAMCL in neuroblastoma via suppressing aerobic glycolysis and targeting PFKL

BACKGROUND: Neuroblastoma (NB) is a common solid malignancy in children that is associated with a poor prognosis. Although the novel small molecular compound Dimethylaminomicheliolide (DMAMCL) has been shown to induce cell death in some tumors, little is known about its role in NB. METHODS: We exami...

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Detalles Bibliográficos
Autores principales: Zhang, Simeng, Hua, Zhongyan, Ba, Gen, Xu, Ning, Miao, Jianing, Zhao, Guifeng, Gong, Wei, Liu, Zhihui, Thiele, Carol J., Li, Zhijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613996/
https://www.ncbi.nlm.nih.gov/pubmed/34819091
http://dx.doi.org/10.1186/s12935-021-02330-y

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