Preventive effect of Ninjin-yoei-to, a Kampo medicine, on amyloid β(1-42)-induced neurodegeneration via intracellular Zn(2+) toxicity in the dentate gyrus

Ninjin-yoei-to (NYT), a Kampo medicine, has ameliorative effects on cognitive dysfunction via enhancing cholinergic neuron activity. To explore an efficacy of NYT administration for prevention and cure of Alzheimer’s disease, here we examined the effect of NYT on amyloid β(1-42) (Aβ(1-42))-induced n...

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Detalles Bibliográficos
Autores principales: Tamano, Haruna, Tokoro, Haruna, Murakami, Daichi, Furuhata, Ryo, Nakajima, Satoko, Saeki, Nana, Katahira, Misa, Shioya, Aoi, Tanaka, Yukino, Egawa, Mako, Takeda, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2021
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614007/
https://www.ncbi.nlm.nih.gov/pubmed/34193681
http://dx.doi.org/10.1538/expanim.21-0044

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