AAV9 transduction mediated by systemic delivery of vector via retro-orbital injection in newborn, neonatal and juvenile mice

Adeno-associated virus (AAV)-based gene therapy is gaining popularity owing to its excellent safety profile and effective therapeutic outcomes in a number of diseases. Intravenous (IV) injection of AAV into the tail vein, facial vein and retro-orbital (RO) venous sinus have all been useful strategie...

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Detalles Bibliográficos
Autores principales: Prabhakar, Shilpa, Lule, Sevda, da Hora, Cintia Carla, Breakefield, Xandra O., Cheah, Pike See
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2021
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614020/
https://www.ncbi.nlm.nih.gov/pubmed/34039790
http://dx.doi.org/10.1538/expanim.20-0186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614020/
https://www.ncbi.nlm.nih.gov/pubmed/34039790
http://dx.doi.org/10.1538/expanim.20-0186

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