PINK1 deficiency impairs osteoblast differentiation through aberrant mitochondrial homeostasis

BACKGROUND: PTEN-induced kinase 1 (PINK1) is a serine/threonine-protein kinase in mitochondria that is critical for mitochondrial quality control. PINK1 triggers mitophagy, a selective autophagy of mitochondria, and is involved in mitochondrial regeneration. Although increments of mitochondrial biog...

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Detalles Bibliográficos
Autores principales: Lee, So-Young, An, Hyun-Ju, Kim, Jin Man, Sung, Min-Ji, Kim, Do Kyung, Kim, Hyung Kyung, Oh, Jongbeom, Jeong, Hye Yun, Lee, Yu Ho, Yang, Taeyoung, Kim, Jun Han, Lim, Ha Jeong, Lee, Soonchul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614054/
https://www.ncbi.nlm.nih.gov/pubmed/34823575
http://dx.doi.org/10.1186/s13287-021-02656-4

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